All perfect praise be to Allah, The Lord of the Worlds. I testify that there is none worthy of worship except Allah, and that Muhammad is His slave and Messenger.
In order to adhere to the rules and regulations of our site, we will limit ourselves to one of the questions, which is the first one.
You did not clarify what you meant by the miserable conditions and the negative things in your life that you do not care about.
If these issues are prohibited matters, then you are obliged to change them and repent from, having committed them. However, if they were merely disliked (not recommended), then it is recommended for you to change them and take care of them. Yet if they are matters which people believe to be miserable but they are Islamically required, then you must be keen on doing them. Nonetheless, if they are permissible matters, then it is equally permissible, to do them or abandon them.
In any case, you must clarify the matters that you do not care about so that we can provide with a detailed answer.
Finally, a Muslim must be ambitious and successful in all fields because Allah loves lofty and honorable matters and hates vile and despicable ones, as in a prophetic narration.
Allah knows best.